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How Do Adipokines Affect Obesity? Obesity and Adipokines

Obesity is defined as a BMI (body mass index) of 25 or more. This excess weight contributes to the development of serious health conditions, damages joints, and compromises the ability to enjoy life. Adipokines are cells in the body that may hold the key to controlling body weight and ending the side effects of obesity. What are adipokines? How do they affect fat storage? How can those suffering from obesity find relief?

Defining Adipokines

Body fat, or adipose fat, forms as a kind of connective tissue that wraps around organs and muscles. Adipose tissues are not inactive collections of cells. Rather, body fat is a metabolically active organ system. This tissue is mainly composed of adipocytes, commonly known as fat cells. Adipokines are a family of hormones and cytokines with both pro- and anti-inflammatory effects that are secreted by adipose tissue. These include tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), leptin, and adiponectin, among others. Pro-inflammatory molecules, such as TNF-α and IL-6, inhibit the production of the anti-inflammatory adipokine adiponectin.

Excess or improperly regulated adipokines is believed to contribute to a number of adverse health effects including type II diabetes, cardiovascular disease, metabolic syndrome, and obesity. Research has suggested (add link) that adipokines play a major role in the inflammation response and how the body uses insulin. A recent study has also shown a link between uncontrolled adipokines and osteoarthritis. Researchers observed that adipokines were used by the body in bone and cartilage functions. Higher adipokine levels are used as an indicator that the patient may suffer from osteoarthritis. Inflammatory conditions like rheumatoid arthritis, systemic lupus, and cardiovascular conditions are also negatively impacted by the presence of certain adipokines.

How Adipokines Affect Obesity The Role of Leptin in Obesity

Leptin is a type of adipokine used in the body’s metabolic functions. The release of leptin inhibits hunger in order to help the body maintain an optimal energy balance. When the body is at rest, leptin is released to discourage the consumption of unnecessary calories. When the body is active, leptin is counteracted by another protein to induce hunger.

Leptin resistance is a common condition in obese persons. The excess adipose fat continues to pump out hormones. Eventually, receptors are no longer able to accurately decipher the messages. Those who suffer from leptin resistance may not feel full enough, regardless of how many calories they consume. If not expended through exercise, those excess calories are stored as fat.

Increased leptin levels are also associated with severe knee injuries. Medical professionals are now using elevated leptin levels to predict the possibility of early post-traumatic knee osteoarthritis. This condition affects younger people who have previously suffered a knee injury. Even after damaged tissues are healed, patients can still experience severe joint pain.

Regulating Leptin may Restore Metabolic Function

Restoring leptin sensitivity can help obesity sufferers control the hormones that may be counteracting their weight loss efforts. Adiposano is a metabolic modulator that regulates leptin in obese patients. In combination with a healthy diet, regular exercise program, and your doctor’s advice, this medical food may support your weight loss efforts in a number of ways:

  • Reduces adipose fat by triggering the body to use it as an energy source. Lean muscle mass is the body’s preferred fuel. Adiposano is believed to preserve muscle while encouraging the body to burn its fat stores.
  • Decrease systemic inflammation. Adiposano may reduce the activities of inflammation-promoting adipokines generated by adipose tissue. This suggests a positive impact on obesity-related diseases.
  • Improves metabolic function. When taken regularly, Adiposano may positively impact insulin sensitivity. It may also decrease the amount of fat stored in the liver. Excess fat in the liver contributes to the inflammation response.

A 3-month course of Adiposano may decrease insulin resistance, blood pressure, blood cholesterol, triglycerides, and systemic inflammation. During that time, you could also see an increase in hunger control and fat metabolism. Adiposano compliments your healthy lifestyle and makes it possible to finally lose the weight.

Is Adiposano the right choice for your weight loss regimen? Contact us for more information on this effective medical food.